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“For it is not cell nuclei, not even individual chromosomes, but certain parts of certain chromosomes from certain cells that must be isolated and collected in enormous quantities for analysis; that would be the precondition for placing the chemist in such a position as would allow him to analyse [the hereditary material] more minutely than [can] the morphologists ... For the morphology of the nucleus has reference at the very least to the gearing of the clock, but at best the chemistry of the nucleus refers only to the metal from which the gears are formed.”
Theodor Boveri“I may finally call attention to the probability that the association of paternal and maternal chromosomes in pairs and their subsequent separation during the reducing division as indicated above may constitute the physical basis of the Mendelian law of heredity.”
Walter S. Sutton“Except for the rare cases of plastid inheritance, the inheritance of all known cofactors can be sufficiently accounted for by the presence of genes in the chromosomes. In a word the cytoplasm may be ignored genetically.”
Thomas Hunt Morgan“They also knew that there was a string of DNA at the end of each chromosome called a telomere, which shortened a tiny bit each time a cell divided, like time ticking off a clock. As normal cells go through life, their telomeres shorten with each division until they’re almost gone. Then they stop dividing and begin to die. This process correlates with the age of a person: the older we are, the shorter our telomeres, and the fewer times our cells have left to divide before they die. By the early nineties, a scientist at Yale had used HeLa to discover that human cancer cells contain an enzyme called telomerase that rebuilds their telomeres. The presence of telomerase meant cells could keep regenerating their telomeres indefinitely. This explained the mechanics of HeLa’s immortality: telomerase constantly rewound the ticking clock at the end of Henrietta’s chromosomes so they never grew old and never died.”
Rebecca Skloot, The Immortal Life of Henrietta Lacks“The test for whether or not you can hold a job should not be the arrangement of your chromosomes.”
Bella Abzug“I use the word “man” loosely. A better description would be “the most beautiful specimen of Homo sapiens sapiens with a set of XY chromosomes to grace the planet Earth at this moment, or any other era, epoch, or age in history.”
Elle Lothlorien, Alice in Wonderland“Richard Nixon has never been one of my favorite people, anyway. For years I've regarded his very existence as a monument to all the rancid genes and broken chromosomes that corrupt the possibilities of the American Dream; he was a foul caricature of himself, a man with no soul, no inner convictions, with the integrity of a hyena and the style of a poison toad.”
Hunter S. Thompson, The Great Shark Hunt: Strange Tales from a Strange Time“The male is a biological accident: the Y (male) gene is an incomplete X (female) gene, that is, it has an incomplete set of chromosomes. In other words, the male is an incomplete female, a walking abortion, aborted at the gene stage. To be male is to be deficient, emotionally limited; maleness is a deficiency disease and males are emotional cripples.”
Valerie Solanas, SCUM Manifesto“Imagine that the genome is a book.There are twenty-three chapters, called CHROMOSOMES.Each chapter contains several thousand stories, called GENES.Each story is made up of paragraphs, called EXTONS, which are interrupted by advertisements called INTRONS.Each paragraph is made up of words, called CODONS.Each word is written in letters called BASES.”
Matt Ridley, Genome: the Autobiography of a Species in 23 Chapters“Individuals are not stable things, they are fleeting. Chromosomes too are shuffled into oblivion, like hands of cards soon after they are dealt. But the cards themselves survive the shuffling. The cards are the genes. The genes are not destroyed by crossing-over, they merely change partners and march on. Of course they march on. That is their business. They are the replicators and we are their survival machines. When we have served our purpose we are cast aside. But genes are denizens of geological time: genes are forever.”
Richard Dawkins, The Selfish Gene