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The first objection to Darwinism is that it is only a guess and was never anything more. It is called a 'hypothesis,' but the word 'hypothesis,' though euphonious, dignified and high-sounding, is merely a scientific synonym for the old-fashioned word 'guess.' If Darwin had advanced his views as a guess they would not have survived for a year, but they have floated for half a century, buoyed up by the inflated word 'hypothesis.' When it is understood that “hypothesis” means 'guess,' people will inspect it more carefully before accepting it.

William Jennings Bryan
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The first objection to Darwinism is that it is only a guess and was never anything more. It is called a 'hypothesis,' but the word 'hypothesis,' though euphonious, dignified and high-sounding, is merely a scientific synonym for the old-fashioned word 'guess.' If Darwin had advanced his views as a guess they would not have survived for a year, but they have floated for half a century, buoyed up by the inflated word 'hypothesis.' When it is understood that “hypothesis” means 'guess,' people will inspect it more carefully before accepting it.

William Jennings Bryan, The Bible Or Evolution
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The existence of matter and energy in the universe did not require the violation of energy conservation at the assumed creation. In fact, the data strongly support the hypothesis that no such miracle occurred. If we regard such a miracle as predicted by the creator hypothesis, then the prediction is not confirmed.

Victor J. Stenger, God: The Failed Hypothesis: How Science Shows That God Does Not Exist
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The only part of evolution in which any considerable interest is felt is evolution applied to man. A hypothesis in regard to the rocks and plant life does not affect the philosophy upon which one's life is built. Evolution applied to fish, birds and beasts would not materially affect man's view of his own responsibilities except as the acceptance of an unsupported hypothesis as to these would be used to support a similar hypothesis as to man. The evolution that is harmful—distinctly so—is the evolution that destroys man's family tree as taught by the Bible and makes him a descendant of the lower forms of life. This ... is a very vital matter.

William Jennings Bryan
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If we consistently act on the optimistic hypothesis, this hypothesis will tend to be realised; whilst by acting on the pessimistic hypothesis we can keep ourselves for ever in the pit of want.

John Maynard Keynes
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To satisfy our doubts . . . it is necessary that a method should be found by which our beliefs may be determined by nothing human, but by some external permanency -- by something upon which our thinking has no effect. . . . Our external permanency would not be external, in our sense, if it was restricted in its influence to one individual. It must be something which affects, or might affect, every man. And, though these affections are necessarily as various as are individual conditions, yet the method must be such that the ultimate conclusion of every man shall be the same. Such is the method of science. Its fundamental hypothesis, restated in more familiar language, is this: There are Real things, whose characters are entirely independent of our opinions about them; those Reals affect our senses according to regular laws, and, though our sensations are as different as are our relations to the objects, yet, by taking advantage of the laws of perception, we can ascertain by reasoning how things really and truly are; and any man, if he have sufficient experience and he reason enough about it, will be led to the one True conclusion. The new conception here involved is that of Reality. It may be asked how I know that there are any Reals. If this hypothesis is the sole support of my method of inquiry, my method of inquiry must not be used to support my hypothesis. The reply is this: 1. If investigation cannot be regarded as proving that there are Real things, it at least does not lead to a contrary conclusion; but the method and the conception on which it is based remain ever in harmony. No doubts of the method, therefore, necessarily arise from its practice, as is the case with all the others. 2. The feeling which gives rise to any method of fixing belief is a dissatisfaction at two repugnant propositions. But here already is a vague concession that there is some one thing which a proposition should represent. Nobody, therefore, can really doubt that there are Reals, for, if he did, doubt would not be a source of dissatisfaction. The hypothesis, therefore, is one which every mind admits. So that the social impulse does not cause men to doubt it. 3. Everybody uses the scientific method about a great many things, and only ceases to use it when he does not know how to apply it. 4. Experience of the method has not led us to doubt it, but, on the contrary, scientific investigation has had the most wonderful triumphs in the way of settling opinion. These afford the explanation of my not doubting the method or the hypothesis which it supposes; and not having any doubt, nor believing that anybody else whom I could influence has, it would be the merest babble for me to say more about it. If there be anybody with a living doubt upon the subject, let him consider it.

Charles Sanders Peirce, The Fixation of Belief
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It may be asked how I know that there are any Reals. If this hypothesis is the sole support of my method of inquiry, my method of inquiry must not be used to support my hypothesis. The reply is this: 1. If investigation cannot be regarded as proving that there are Real things, it at least does not lead to a contrary conclusion; but the method and the conception on which it is based remain ever in harmony. No doubts of the method, therefore, necessarily arise from its practice, as is the case with all the others. 2. The feeling which gives rise to any method of fixing belief is a dissatisfaction at two repugnant propositions. But here already is a vague concession that there is some one thing which a proposition should represent. Nobody, therefore, can really doubt that there are Reals, for, if he did, doubt would not be a source of dissatisfaction. The hypothesis, therefore, is one which every mind admits. So that the social impulse does not cause men to doubt it. 3. Everybody uses the scientific method about a great many things, and only ceases to use it when he does not know how to apply it. 4. Experience of the method has not led us to doubt it, but, on the contrary, scientific investigation has had the most wonderful triumphs in the way of settling opinion. These afford the explanation of my not doubting the method or the hypothesis which it supposes; and not having any doubt, nor believing that anybody else whom I could influence has, it would be the merest babble for me to say more about it. If there be anybody with a living doubt upon the subject, let him consider it.

Charles Sanders Peirce, The Fixation of Belief
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Since belief is measured by action, he who forbids us to believe religion to be true, necessarily also forbids us to act as we should if we did believe it to be true. The whole defence of religious faith hinges upon action. If the action required or inspired by the religious hypothesis is in no way different from that dictated by the naturalistic hypothesis, then religious faith is a pure superfluity, better pruned away, and controversy about its legitimacy is a piece of idle trifling, unworthy of serious minds. I myself believe, of course, that the religious hypothesis gives to the world an expression which specifically determines our reactions, and makes them in a large part unlike what they might be on a purely naturalistic scheme of belief.

William James, The Will to Believe, Human Immortality and Other Essays in Popular Philosophy
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Faith is the choice of the nobler hypothesis.' Not the noblest, one never knows what that is. But the nobler, the best one can see when the choice is made.

Robert K. Greenleaf, Servant As Leader
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There is no justifiable prediction about how the hypothesis will hold up in the future its degree of corroboration simply is a historical statement describing how severely the hypothesis has been tested in the past.

Robert Nozick
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Many people assert that this abandonment of the god hypothesis means the abandonment of all religion and all moral sanctions. This is simply not true. But it does mean, once our relief at jettisoning an outdated piece of ideological furniture is over, that we must construct something to take its place.

Julian Huxley, Essays of a Humanist
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