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The theoretical determination of the fine structure constant is certainly the most important of the unsolved problems of modern physics. We believe that any regression to the ideas of classical physics (as, for instance, to the use of the classical field concept)cannot bring us nearer to this goal. To reach it, we shall, presumably, have to pay with further revolutionary changes of the fundamental concepts of physics with a still farther digression from the concepts of the classical theories.

Wolfgang Pauli
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The unsolved problems of the physical world now seem even more formidable than those solved in the twentieth century. Though in application it works splendidly, we do not even understand the physical meaning of quantum mechanics, much less how it might be united with general relativity.We don't know why the dimensionless constants (ratios of masses of elementary particles, ratios of strength of gravitational to electric forces, fine structure constant, etc.) have the values they do, unless we appeal to the implausible anthropic principle, which seems like a regression to Aristotelian teleology.

Gerald Holton, Physics, the Human Adventure: From Copernicus to Einstein and Beyond
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QED [quantum electrodynamics] reduces ... "all of chemistry and most of physics," to one basic interaction, the fundamental coupling of a photon to electric charge. The strength of this coupling remains, however, as a pure number, the so-called fine-structure constant, which is a parameter of QED that QED itself is powerless to predict.

Frank Wilczek, Longing for the Harmonies: Themes and Variations from Modern Physics
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Medical physics is an applied area of physics.

John Cameron
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In the beginning, there was physics. "Physics" describes how matter, energy, space, and time behave and interact with one another. The interplay of these characters in our cosmic drama underlies all biological and chemical phenomena. Hence everything fundamental and familiar to us earthlings begins with, and rests upon, the laws of physics. When we apply these laws to astronomical settings, we deal with physics writ large, which we call astrophysics.

Neil deGrasse Tyson
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It is hardly surprising that there are more things in heaven and earth, dear reader, than have been dreamed of in our philosophy - or in our physics.

Carlo Rovelli, Seven Brief Lessons on Physics
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At one point in the story, following a brazen daytime bank robbery, Electro is shown escaping from the authorities by climbing up the side of a building, as easily as Spider-Man . . . we see one observer exclaim, "Look!! That strangely-garbed man is racing up the side of the building!" A second man on the street picks up the narrative: "He's holding on to the iron beams in the building by means of electric rays—using them like a magnet!! Incredible!"There are three feelings inspired by this scene. The first is wonder as to why people rarely use the phrase "strangely-garbed" anymore. The second is nostalgia for the bygone era when pedestrians would routinely narrate events occurring in front of them, providing exposition for any casual bystander. And the third is pleasure at the realization that Electro's climbing this building is actually a physically plausible use of his powers.

James Kakalios, The Physics of Superheroes
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...every physicist knows that the laws of physics can be used to build a gun or a bicycle; physics does not dictate a specific use for its laws. To that extent, it should be obvious that the laws of physics are incomplete in predicting everything that occurs in nature—from Moral Materialism

Ashish Dalela
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Physics is the ultimate intellectual adventure, the quest to understand the deepest mysteries of our Universe. Physics doesn’t take something fascinating and make it boring. Rather, it helps us see more clearly, adding to the beauty and wonder of the world around us. When I bike to work in the fall, I see beauty in the trees tinged with red, orange and gold. But seeing these trees through the lens of physics reveals even more beauty.

Max Tegmark, Our Mathematical Universe: My Quest for the Ultimate Nature of Reality
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We also find *physics*, in the widest sense of the word, concerned with the explanation of phenomena in the world; but it lies already in the nature of the explanations themselves that they cannot be sufficient. *Physics* is unable to stand on its own feet, but needs a *metaphysics* on which to support itself, whatever fine airs it may assume towards the latter. For it explains phenomena by something still more unknown than are they, namely by laws of nature resting on forces of nature, one of which is also the vital force. Certainly the whole present condition of all things in the world or in nature must necessarily be capable of explanation from purely physical causes. But such an explanation―supposing one actually succeeded so far as to be able to give it―must always just as necessarily be burdened with two essential imperfections (as it were with two sore points, or like Achilles with the vulnerable heel, or the devil with the cloven foot). On account of these imperfections, everything so explained would still really remain unexplained. The first imperfection is that the *beginning* of the chain of causes and effects that explains everything, in other words, of the connected and continuous changes, can positively *never* be reached, but, just like the limits of the world in space and time, recedes incessantly and *in infinitum*. The second imperfection is that all the efficient causes from which everything is explained always rest on something wholly inexplicable, that is, on the original *qualities* of things and the *natural forces* that make their appearance in them. By virtue of such forces they produce a definite effect, e.g., weight, hardness, impact, elasticity, heat, electricity, chemical forces, and so on, and such forces remain in every given explanation like an unknown quantity, not to be eliminated at all, in an otherwise perfectly solved algebraical equation. Accordingly there is not a fragment of clay, however little its value, that is not entirely composed of inexplicable qualities. Therefore these two inevitable defects in every purely physical, i.e., causal, explanation indicate that such an explanation can be only *relatively* true, and that its whole method and nature cannot be the only, the ultimate and hence sufficient one, in other words, cannot be the method that will ever be able to lead to the satisfactory solution of the difficult riddles of things, and to the true understanding of the world and of existence; but that the *physical* explanation, in general and as such, still requires one that is *metaphysical*, which would furnish the key to all its assumptions, but for that very reason would have to follow quite a different path. The first step to this is that we should bring to distinct consciousness and firmly retain the distinction between the two, that is, the difference between *physics* and *metaphysics*. In general this difference rests on the Kantian distinction between *phenomenon* and *thing-in-itself*. Just because Kant declared the thing-in-itself to be absolutely unknowable, there was, according to him, no *metaphysics* at all, but merely immanent knowledge, in other words mere *physics*, which can always speak only of phenomena, and together with this a critique of reason which aspires to metaphysics."―from_The World as Will and Representation_. Translated from the German by E. F. J. Payne. In Two Volumes, Volume II, pp. 172-173

Arthur Schopenhauer
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