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Let’s imagine a running washing machine. Let’s imagine the dirty clothes in the machine and how the liquid detergent is getting the dirt out of clothes and draining it to the waste outlet. Now imagine brain surrounded by a large pool of cleaning fluid called CSF (cerebrospinal fluid). Imagine CSF pulling the wastes from inside the brain and draining it into the blood, which routes it to the waste outlets. CSF clears waste many times faster in sleeping brain than in the waking brain.

Pawan Mishra
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Insomnia is a variant of Tourette's--the waking brain races, sampling the world after the world has turned away, touching it everywhere, refusing to settle, to join the collective nod. The insomniac brain is a sort of conspiracy theorist as well, believing too much in its own paranoiac importance--as though if it were to blink, then doze, the world might be overrun by some encroaching calamity, which its obsessive musings are somehow fending off.

Jonathan Lethem, Motherless Brooklyn
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