“I don't think there is such a thing as pure imagination. I think it's a combination of memory and invention.”

“You know that thing people say, 'poetry is the hardest, stories are the second hardest, novels are the easiest?' I'm here to tell you that novels are the hardest. Writing a novel is unbelievably difficult. It's nightmarish.”

“There has always been a tension in my life between the romantic and the practical. I can't hole myself up in a cabin and write down ideas for the rest of my life. I also need to be able to clean out a dog bite.”

“I don't think there is such a thing as pure imagination. I think it's a combination of memory and invention.”

“The historical background is one of the easier aspects of writing a novel. Far more difficult is dreaming up the smaller, character-based scenes, scenes that rise entirely from one's own imagination.”

“In medical school, you're taught to write in this convoluted, Latinate way. I knew the vocabulary as well as anyone, but I would write kidney instead of nephric. I insisted on using English.”

“When I went for my medical school interview, I had an old paperback of 'Henderson the Rain King' in the pocket of my coat. I was wearing the best clothes I had - a pair of cords and a sport coat - but when I got to the office, all the other interviewees were lined up in their black suits.”

“I don't want to be movie-star famous. I want to move people with my writing.”

“As soon as we conform anything to language, we’ve changed it. Use a word and you’ve altered the world. The poets know this. It’s what they try so hard to avoid.”