“I never was someone who was at ease with happiness.”

“This was the tricky bit. The really tricky bit, trickiness cubed.”

“Riding my motorcycle around L.A. is like my own video game. But unlike many folks at the wheel, I am occupied with getting where I'm going and keeping myself safe. Most people are applying makeup, texting, and checking out the beauty in the next car.”

“Some people are drawn naturally - there are natural guitarists, and there are natural piano players, and I think guitar implies travel, a sort of footloose gypsy existence. You grab your bag and you go to the next town.”

“I think my father gave me a great reverence for medical science. He was about as opposite to the personality of House as one could imagine. He was polite and easygoing, and would have gone to great lengths to make his patients feel attended to and heard and sympathized with.”

“Driving a motorcycle is like flying. All your senses are alive. When I ride through Beverly Hills in the early morning, and all the sprinklers have turned off, the scents that wash over me are just heavenly. Being House is like flying, too. You're free of the gravity of what people think.”

“I never was someone who was at ease with happiness.”

“I had too many things to say, and too small a brain to sort them out with.”

“It's a terrible thing, I think, in life to wait until you're ready. I have this feeling now that actually no one is ever ready to do anything. There's almost no such thing as ready. There's only now. And you may as well do it now. I mean, I say that confidently as if I'm about to go bungee jumping or something--I'm not. I'm not a crazed risk taker. But I do think that, generally speaking, now is as good a time as any.”

“I would cling to unhappiness because it was a known, familiar state. When I was happier, it was because I knew I was on my way back to misery. I've never been convinced that happiness is the object of the game. I'm wary of happiness.”

“This was all horribly wrong. This was red wine with fish. This was a man wearing a dinner jacket and brown shoes. This was as wrong as things get.”